Prosecutors allege Maxwell and Epstein recruited the underage girl to perform massages that turned sexual at Epstein's Palm Beach residence. In exchange, they paid her hundreds of dollars in cash for each encounter, prosecutors allege.
The new charges against Maxwell allege she engaged in sex trafficking of a minor multiple times more recently, from 2001 to 2004. Prosecutors also charged Maxwell with one count of sex trafficking conspiracy.
The indictment alleges that Maxwell interacted with the 14-year-old girl on multiple occasions in Palm Beach and was aware that the girl was under 18 at the time. The indictment also alleges that Maxwell encouraged and enticed the girl to recruit other girls to perform "sexualized massages" for Epstein.
In a letter filed with the court, prosecutors said a grand jury sitting in Manhattan returned the charges. Prosecutors also wrote that they will begin producing for Maxwell's attorneys copies of non-testifying witness statements by April 12, 2021, approximately three months before her trial is scheduled to begin.
"This production will include the statements of more than 250 witnesses related to the investigation of Jeffrey Epstein and his associates in the Government's possession whom the Government does not currently expect to call to testify at trial," wrote Audrey Strauss, the US attorney for the Southern District of New York.
Last week, Nathan denied Maxwell's third attempt at receiving bail pending her trial citing, "considerable doubt as to the defendant's willingness to abide by any set of conditions of release."
Maxwell is being held at the Metropolitan Detention Center in Brooklyn.
Epstein, who pleaded not guilty, died on August 10, 2019, while awaiting trial in federal prison.
CNN's Steve Almasy and Sonia Moghe contributed to this report.