Brilliant midfielder Nick Daicos has continued his red-hot form to lead AFL heavyweights Collingwood to a 66-point thrashing of West Coast amid injury carnage for both sides.

As the Magpies' makeshift forward line lost Jeremy Howe to a groin issue, Daicos pulled the strings in the engine room during a 15.13 (103) to 5.7 (37) victory at Marvel Stadium on Sunday.

The smooth-moving ball-winner racked up 36 disposals, 17 contested possessions, seven clearances, seven tackles and a goal as Collingwood improved to 5-1-3 ahead of a clash with Adelaide.

The Magpies also secured a much-needed percentage boost, lifting nine points to push above 100 for the first time this season.

But the win came at a cost, with Howe (groin) and Harvey Harrison (ankle) hurt during the first quarter.

Former St Kilda midfielder Jack Bytel, who was substituted in for Howe on his Magpies debut, also failed to finish the match because of concussion after a collision with Jack Darling.

West Coast lost experienced defender Jeremy McGovern (ribs) and speedster Jack Petruccelle (ankle) to injuries on a dirty day.

Daicos had plenty of support through brother Josh Daicos (28 disposals), Scott Pendlebury (28), Jack Crisp (32) and John Noble (25) in a dominant Collingwood performance that started in the middle.

The Pies won a lop-sided clearance count 38-25, including a 16-6 annihilation at centre bounces.

Finlay Macrae and Reef McInnes kicked career-high tallies of three goals each, and Bobby Hill added two more, while mature-age recruit Joe Richards impressed on debut with 1.2 and three goal assists from 18 disposals.

Liam Duggan (27 disposals) and Alex Witherden (30) battled on for West Coast and emerging star Harley Reid (17) took a huge early mark on Billy Frampton's back, but it was a rare highlight for the visitors.

AAP