Richmond have copped another AFL hammering, the Brisbane Lions re-writing the record books as they filled their boots in a 119-point Gabba mauling.

The injury-ravaged Tigers conceded the first 10 goals on Saturday night, the hosts in no mood for sympathy as they amassed a percentage-boosting 26.7 (163) to 6.8 (44) win.

It was the Lions' biggest score since coach Chris Fagan arrived in 2017 and second-largest victory since the club merger, behind a 141-point drubbing of Adelaide in 2004.

Lions forwards Charlie Cameron (five goals), Kai Lohmann (five goals) and Joe Daniher (three goals, two assists) feasted, and Dayne Zorko (35 disposals) continued his prolific season.

The hosts kicked four goals in the first 12 minutes, Lachie Neale (36 disposals, six goal assists) picking the Tigers apart with ease.

There was no relenting from a side that had lost their first three Gabba games this season and were 2-5 before two wins and a draw from their past three games.

Cameron played on to kick his third as Brisbane passed 100 points midway through the third term, before two straight Tigers goals brought brief respite in front of 27,200 fans.

The Lions rattled away again, Daniher's third major totally accidental when his attempt to pop a pass to Hugh McCluggage bounced through an open goal.

Already nursing 15 men on their injury list, Richmond will hope Mykelti Lefau and Rhyan Mansell aren't the latest to join them.

Lefau kicked a goal then copped a stray knee to the face as he descended from a marking contest, the former NRL hopeful subbed out before halftime.

Mansell then came off second-best in a four-way, mid-air collision, his hulking captain Toby Nankervis the culprit in friendly fire that sent him wobbling to the bench.

The second of Cam Rayner's three goals made it a 102-point margin at the final break, teenage rookie Logan Morris (two goals) among 12 individual Brisbane goalkickers.

Dustin Martin (16 touches, three tackles, two clearances) spent most of the final quarter on the bench and had little to work with when on the ground, bizarrely handballing in the second quarter when a clear path to goal opened.

Daniel Rioli (25 touches) was the Tigers' top ball-winner, the visitors winning centre clearances but being outmarked 164-66.

Defeat dropped the Tigers to 1-9, with in-form Essendon their next test at the MCG on Saturday.

AAP