WA Police have charged a man with murder over the death of a cyclist on Friday afternoon, as they probe a potential property dispute between the two parties. 

WARNING: This story contains details that may distress some readers.

The victim was riding on Lion Street in Carlisle at about 1:45pm when it's alleged he was approached by a 27-year-old man driving a grey Kia Carnival station sedan.

Police allege the cyclist was hit by the Kia, and dragged under the vehicle.

Following the incident, police cordoned off a wide area either side of the crash scene, with shoes, boxes and other items left scattered on the road.

Speaking at a press conference on Saturday afternoon, WA Police Detective Inspector David Gorton said preliminary investigations suggested the man could have been dragged by the vehicle for "potentially in excess of 30 metres".

The cyclist was taken to Royal Perth Hospital, where he later died.

Detective Inspector Gorton said police had been called to the scene because of the "driving behaviour" of the man in the Kia Carnival, and said he was "apprehended quickly".

"That individual has now been charged with murder and will appear in court tomorrow," he said.

"Police will allege this was a deliberate act."

Detective Inspector Gorton also said police were probing a possible property dispute between the parties. 

"We are looking into what we believe was an incident the previous day," he said.

"We believe that may have involved a personal property item, however investigations are still ongoing.

"We just want to reiterate to members of the public that if you are a victim of crime, no matter how serious the incident is, we urge to contact WA Police if you feel that you need assistance."

Detective Inspector Gorton said the charged man was not alone in the Kia, and that "family and friends" in the vehicle had been "spoken to as witnesses".