Emergency crews are battling rough terrain and unpredictable weather in a bid to rescue a climber who fell last night in the northern part of the Grampians National Park in Victoria's west.

The man, in his early 20s, was climbing at Mount Stapylton when he fell about 2.5 metres and sustained back injuries.

He is in a stable condition.

CFA commander of the operation Lindsay Barry said the injured climber was treated by Ambulance Victoria's wilderness response team before multi-agency rescue crews arrived this morning.

"He's conscious and coherent," Commander Barry said.

"Ambulance Victoria is staying with him and doing a great job to stabilise him and keep him comfortable until we can get the rescue crews in there to get him out."

He said the rocky terrain as well as fog and rain had prevented the crews from using aircraft.

Beautiful but dangerous

"We're utilising ground crew and specialised rope technicians to walk in and set up a roping system and assist in lowering the patient down and then we'll walk out, Commander Berry said.

He said it was about a 90-minute walk in from the car park, where crews were stationed to reach the injured man, but this was compounded having to carry rescue equipment like stretchers.

"As beautiful as the Grampians are, it's quite a rugged environment and the weather conditions today are adding to some of the complications we've got to deal with like slippery rocks and steep terrain," Commander Barry said.

"It's nothing beyond us that's for sure.

"All agencies train for situation exactly like this and I'm very confident we'll have a successful outcome.

"It's very much a dynamic and changing situation."

Victoria Police is leading the operation with CFA, SES FRV and Ambulance Victoria assisting.